A Case of Acute Eosinophilic Pneumonia Associated with Intramuscular Administration of Progesterone Following In Vitro Fertilization.
10.4046/trd.2009.67.6.556
- Author:
Sung Keun PARK
1
;
Byoung Ho CHOI
;
Su Yeon CHON
;
Yu Jin KIM
;
Sun Young KYUNG
;
Sang Pyo LEE
;
Sung Hwan JEONG
;
Jeong Woong PARK
Author Information
1. Department of Internal Medicine, Gachon University of Medicine and Science, Incheon, Korea. jwpark@gilhospital.com
- Publication Type:In Vitro ; Case Report
- Keywords:
Pulmonary Eosinophilia;
Progesterone;
Eosinophilia
- MeSH:
Adult;
Anoxia;
Cough;
Dyspnea;
Emergencies;
Eosinophilia;
Eosinophils;
Female;
Fertilization in Vitro;
Fever;
Humans;
Lung;
Luteal Phase;
Progesterone;
Pulmonary Eosinophilia;
Tachypnea;
Thorax
- From:Tuberculosis and Respiratory Diseases
2009;67(6):556-559
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Acute eosinophilic pneumonia (AEP) is characterized by idiopathic acute febrile illness, diffuse pulmonary infiltration, severe hypoxemia, and pulmonary eosinophilia. We report a case of AEP associated with intramuscular administration of progesterone as luteal phase support after in vitro fertilization. A 33-year-old woman presented to our emergency room with tachypnea and hypoxemia, complaining of fever and cough for 4 days, and dyspnea for 2 days. The symptoms began 9 days after the first injection of progesterone. Chest radiograph showed bilateral infiltrates, located predominantly in the periphery of the lungs, with blunting of the costophrenic angle. Symptoms and chest radiograph dramatically improved after corticosteroid therapy and shifting the progesterone from an intramuscular form of administration to a vaginal form of administration.
