The Korean Gastric Cancer Cohort Study: Study Protocol and Brief Results of a Large-Scale Prospective Cohort Study.
10.5230/jgc.2016.16.3.182
- Author:
Bang Wool EOM
1
;
Young Woo KIM
;
Byung Ho NAM
;
Keun Won RYU
;
Hyun Yong JEONG
;
Young Kyu PARK
;
Young Joon LEE
;
Han Kwang YANG
;
Wansik YU
;
Jeong Hwan YOOK
;
Geun Am SONG
;
Sei Jin YOUN
;
Heung Up KIM
;
Sung Hoon NOH
;
Sung Bae PARK
;
Doo Hyun YANG
;
Sung KIM
Author Information
1. Gastric Cancer Branch, Division of Translational & Clinical Research I, National Cancer Center, Goyang, Korea. gskim@ncc.re.kr
- Publication Type:Original Article
- Keywords:
Stomach neoplasms;
Cohort studies;
Korea;
Quality of life
- MeSH:
Cohort Studies*;
Diet;
Drug Therapy;
Humans;
Korea;
Male;
Occupational Groups;
Prospective Studies*;
Quality of Life;
Stomach Neoplasms*
- From:Journal of Gastric Cancer
2016;16(3):182-190
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: This study aimed to establish a large-scale database of patients with gastric cancer to facilitate the development of a national-cancer management system and a comprehensive cancer control policy. MATERIALS AND METHODS: An observational prospective cohort study on gastric cancer was initiated in 2010. A total of 14 cancer centers throughout the country and 152 researchers were involved in this study. Patient enrollment began in January 2011, and data regarding clinicopathological characteristics, life style-related factors, quality of life, as well as diet diaries were collected. RESULTS: In total, 4,963 patients were enrolled until December 2014, and approximately 5% of all Korean patients with gastric cancer annually were included. The mean age was 58.2±11.5 years, and 68.2% were men. The number of patients in each stage was as follows: 3,394 patients (68.4%) were in stage IA/B; 514 patients (10.4%), in stage IIA/B; 469 patients (9.5%), in stage IIIA/B/C; and 127 patients (2.6%), in stage IV. Surgical treatment was performed in 3,958 patients (79.8%), endoscopic resection was performed in 700 patients (14.1%), and 167 patients (3.4%) received palliative chemotherapy. The response rate for the questionnaire on the quality of life was 95%; however, diet diaries were only collected for 27% of patients. CONCLUSIONS: To provide comprehensive information on gastric cancer for patients, physicians, and government officials, a large-scale database of Korean patients with gastric cancer was established. Based on the findings of this cohort study, an effective cancer management system and national cancer control policy could be developed.
