A Case of Cystadenocarcinoma of the Pancreas in a Patient with Autosomal Dominant Polycystic Kidney Disease.
- Author:
Soo Youn LEE
1
;
Young Jun YANG
;
Dong Seok JANG
;
Young Mo LEE
;
Ki Ryang NA
;
Byung Seok LEE
;
Kang Wook LEE
;
Young Tai SHIN
Author Information
1. Division of Nephrology, Department of Internal Medicine, College of Medicine, Chungnam National University, Daejeon, Korea. kwlee@cnu.ac.kr
- Publication Type:Case Report
- Keywords:
Polycystic kidney diseases;
Pancreatic neoplasms;
Cystadenocarcinoma
- MeSH:
Anorexia;
Cisplatin;
Cystadenocarcinoma*;
Diagnosis;
Disease Progression;
Drug Therapy, Combination;
Humans;
Intracranial Aneurysm;
Liver;
Lung;
Middle Aged;
Mitral Valve Prolapse;
Neoplasm Metastasis;
Pancreas*;
Pancreatic Neoplasms;
Polycystic Kidney Diseases;
Polycystic Kidney, Autosomal Dominant*;
Spleen;
Tomography, X-Ray Computed;
Weight Loss
- From:Korean Journal of Nephrology
2007;26(4):465-468
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Polycystic kidney disease is an autosomal dominant disease that may be associated with liver and pancretic cysts. Mitral valve prolapse and intracranial berry aneurysms are also well-known manifestations of autosomal dominant polycystic kidney disease (ADPKD). Cystadenocarcinoma of the pancreas is uncommon and accounts for only 1% of primary pancreatic malignancies. Few cases were reported to have an association of ADPKD and pancreatic malignancies. We report a 63-year-old man with ADPKD who was admitted to our hospital with anorexia and severe weight loss. After abdominal CT and histologic examination, he was diagnosed as pancreatic cystadenocarcinoma with lung, spleen, and liver metastasis. To prolong the life of the patient, we tried gemcitabine and cisplatin combination chemotherapy. But the patient died 2 months after diagnosis due to the disease progression.
