A Case of Primary Focal Segmental Glomerulosclerosis in an Adolescent Patient with Type 1 Diabetes.
- Author:
Seung Hyon BAEK
1
;
Ah Reum KWON
;
Hyeon Joo JEONG
;
Min Ju KIM
;
Hyun Wook CHAE
;
Ho Seong KIM
;
Duk Hee KIM
Author Information
1. Department of Pediatrics, Yonsei University College of Medicine, Korea.
- Publication Type:Case Report
- Keywords:
Diabetes mellitus, type 1;
Diabetic nephropathy;
Glomerulosclerosis focal segmental
- MeSH:
Adolescent;
Adrenal Cortex Hormones;
Biopsy;
Diabetes Mellitus, Type 1;
Diabetic Nephropathies;
Diabetic Retinopathy;
Edema;
Glomerulosclerosis, Focal Segmental;
Hemoglobins;
Humans;
Liver;
Nephrosis;
Peptidyl-Dipeptidase A
- From:Journal of Korean Society of Pediatric Endocrinology
2010;15(3):203-206
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Diabetic nephropathy is a common and serious complication in diabetic patients. Renal diseases other than diabetic nephropathy (non-diabetic nephropathy) can occur in diabetic patients with nephrosis. The presence of non-diabetic nephropathy is noted in type 2 diabetes patients, but no data exists for type 1 diabetes. In this report we describe the case of a 15-year-old girl with type 1 diabetes mellitus, who presented with an acute elevation of urinary microalbumin excretion, general edema, and liver enzyme elevation. She had shown microalbuminuria about 3 years earlier, as well as an uncontrolled hemoglobin A1c level, but she had no diabetic retinopathy and neuropathy. A renal biopsy was conducted, and she was diagnosed with primary focal segmental glomerulosclerosis. She was treated with corticosteroids and an angiotensin converting enzyme inhibitor.