A Case of Idiopathic Lymphocytoma Cutis.
10.5021/ad.2004.16.2.71
- Author:
Ji Eun KIM
;
Mi Yeon KIM
;
Young Min PARK
;
Hyung Ok KIM
- Publication Type:Case Report
- Keywords:
Cutaneous B cell pseudolymphoma;
Idiopathic lymphocytoma cutis;
Immunoglobulin gene rearragnement
- MeSH:
Genes, Immunoglobulin;
Germinal Center;
Lymph Nodes;
Lymphocytes;
Lymphoid Tissue;
Lymphoma, B-Cell;
Pseudolymphoma*;
Skin
- From:Annals of Dermatology
2004;16(2):71-75
- CountryRepublic of Korea
- Language:English
-
Abstract:
The pseudolymphoma of the skin has the architectural and cytological features of a neoplastic proliferation of lymphoid tissue but pursue a benign course. Cutaneous B cell pseudolymphoma (CBPL) shares many histopathologic and clinical features with cutaneous B cell lymphoma (CBCL). Therefore, the differentiation between CBPL and CBCL is often very difficult, but it is important because each of them has a different therapeutic consequence. Recently, immunoglobulin gene rearrangement is considered as a reliable technique for differentiation of CBPL with CBCL. We herein report a case of idiopathic lymphocytoma cuffs, showing a typical nodular infiltrate of lymphocytes that formed a follicular germinal center resembling reactive lymph nodes with numerous tingible bodies, and that revealed a polyclonality in the immunoglobulin gene rearrangement.