Hepatocellular Carcinoma Localized in the Bile Duct Lumen: Two case report.
10.3348/jkrs.1998.39.4.763
- Author:
Kyeung Kug BAE
1
;
Jay Chun CHANG
Author Information
1. Department of Diagnostic Radiology, Yeungnam University, School of Medicine.
- Publication Type:Case Report
- Keywords:
Liver neoplasms, CT;
Bile ducts, neoplasms
- MeSH:
alpha-Fetoproteins;
Angiography;
Bile Ducts*;
Bile*;
Carcinoma, Hepatocellular*;
Cholangiography;
Mucous Membrane;
Tomography, X-Ray Computed
- From:Journal of the Korean Radiological Society
1998;39(4):763-767
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Intrabile duct tumor growth of hepatocellular carcinoma is an uncommon manifestation, but intraluminal bileduct hepatocellular carcinoma without primary hepatic parenchymal lesions is extremely rare. To our knowledge,only a few case reports have been published. We encountered two cases of primary hepatocellular carcinoma arisingin the bile duct; serum alpha-fetoprotein levels were within the normal limits. Both showed the followingcharacteristic radiologic features: 1) Cholangiography revealed filling defects within the dilated bile duct; 2)two-phase abdominal CT showed enhancement during the arterial-dominant phase and washout during the tissueequilibrium phase, as in typical HCC; and 3) hepatic arteriography revealed hypervascular tumor staining. Surgerywas performed and the resected specimen showed no detectable primary hepatic parenchymal mass; on the basis of thepathologic findings, intraluminal bile duct hepatocellular carcinoma was confirmed. We cautiously assume that thispeculiar type of HCC may arise primarily from bile duct mucosa.
