Effect of Doxapram Hydrochloride on Respiration after General Anesthesia.
10.4097/kjae.1972.5.2.147
- Author:
Tae Suck SHIN
1
;
Kyu Suck SUH
;
Dong Won LIM
;
Sang Ho JIN
Author Information
1. Department of Anesthesiology, School of Medicine, Kyung Hee University, Seoul, Korea.
- Publication Type:Original Article
- MeSH:
Anesthesia, General*;
Doxapram*;
Electrocardiography;
Respiration*;
Thiopental
- From:Korean Journal of Anesthesiology
1972;5(2):147-150
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The effect of a new analeptic, doxapram hydrochloride, on respiration has been studied in ten subjects anesthetized with thiopental or with nitrous oxide-oxygen-halothane. The results are as follows: 1) Respiratory stimulation was more pronounced in the group anesthetized with thiopental than that with nitrous oxide-oxygen-halothane. 2) The stimulatory effect lasted for four minutes. Subjects who received multiple doses of the drug, however, showed a cumulative effect. 3) Most cases showed moderate hypertensive effect and brief electrocardiographic change was observed in one of the ten.
