A Case with Changes in Autoantibodies with Mimicking Specificity in a Patient with Hepatocellular Carcinoma.
10.17945/kjbt.2017.28.2.177
- Author:
Hyeon Ho LIM
1
;
Kyeong Hee KIM
;
Gi Cheol JEONG
;
Gyu Dae AN
;
Kwang Sook WOO
;
Jin Yeong HAN
;
Jeong Man KIM
Author Information
1. Department of Laboratory Medicine, Dong-A University College of Medicine, Busan, Korea. progreen@dau.ac.kr
- Publication Type:Case Report
- Keywords:
Autoantibody;
Mimicking specificity;
Autoimmunization;
Transfusion
- MeSH:
Aged;
Agglutination;
Autoantibodies*;
Carcinoma, Hepatocellular*;
Humans;
Hypoglycemia;
Male;
Sensitivity and Specificity*
- From:Korean Journal of Blood Transfusion
2017;28(2):177-182
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Changes in autoantibodies with mimicking specificity for Rh antigens are quite rare. Here, we report a 73-year-old male patient with hepatocellular carcinoma that showed changes in the autoantibodies with mimicking specificity. He was admitted to our hospital with mental alterations and hypoglycemia. The antibody identification test for RBC transfusion showed a pattern of agglutination, suggesting anti-E alloantibody and anti-c autoantibody. The patient was then diagnosed with hepatocellular carcinoma, and after 18 months, the antibody identification test showed a different pattern of agglutination, suggesting anti-E alloantibody and anti-C autoantibody. We recommend a careful evaluation to make sure an appropriate transfusion is performed when encountering fluctuating autoantibodies with mimicking specificity.
