A Case of Non-Hodgkin's Lymphoma of the Ocular Adnexa and Lung in a 17-year-old with Primary Sjogren's Syndrome.
- Author:
Sang Hyun KIM
1
;
Han Ah LEE
;
Seung Woon PARK
;
Kang Won LEE
;
Young Ho SEO
;
Jae Hoon KIM
;
Sung Jae CHOI
;
Young Ho LEE
;
Jong Dae JI
;
Gwan Gyu SONG
Author Information
- Publication Type:Case Report
- Keywords: Sjogren's syndrome; Lymphoma; Conjunctiva; Lung
- MeSH: Adolescent*; Conjunctiva; Exocrine Glands; Eyelids; Female; Humans; Korea; Lung*; Lymphoma; Lymphoma, Non-Hodgkin*; Mouth; Sjogren's Syndrome*
- From:Journal of Rheumatic Diseases 2016;23(1):61-65
- CountryRepublic of Korea
- Language:English
- Abstract: Sjogren's syndrome (SS) is a chronic autoimmune disorder characterized by lymphocyte-mediated destruction of exocrine glands, which produces classical symptoms of dry eyes and dry mouth. Aside from the clinical manifestations associated with exocrine glands, extraglandular features of SS include a major long-term concern for development of lymphoma. The lifetime risk of non-Hodgkin's lymphoma (NHL) in an SS patient is approximately 5% to 10%, 20 times higher than that of the normal population. This case report describes a rare occurrence of NHL in the eyelid and lung of an adolescent female with SS, whose disease activity had been monitored closely. This is the first reported case in Korea.
