Morphologic Changes in Acute Central Serous Chorioretinopathy Using Spectral Domain Optical Coherence Tomography.
10.3341/kjo.2012.26.5.347
- Author:
Hyung Chan KIM
1
;
Won Bin CHO
;
Hyewon CHUNG
Author Information
1. Department of Ophthalmology, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea. eyekim@kuh.ac.kr
- Publication Type:Original Article
- Keywords:
Central serous chorioretinopathy;
Fluorescein angiography;
Indocyanine green angiography;
Leakage site;
Spectral domain optical coherence tomography
- MeSH:
Acute Disease;
Adult;
Central Serous Chorioretinopathy/*pathology;
Female;
Fluorescein Angiography;
Humans;
Indocyanine Green/diagnostic use;
Male;
Microscopy, Confocal;
Middle Aged;
Retrospective Studies;
*Tomography, Optical Coherence
- From:Korean Journal of Ophthalmology
2012;26(5):347-354
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: To investigate morphologic changes of acute central serous chorioretinopathy (CSC) using spectral domain optical coherence tomography (SD-OCT) and confocal scanning laser ophthalmoscopy. METHODS: This retrospective study included 63 eyes of 63 patients with unilateral acute CSC. All patients underwent simultaneous SD-OCT and fluorescein angiography examination using Spectralis HRA+OCT. RESULTS: The external limiting membrane could be seen on SD-OCT, although the junction between photoreceptor inner and outer segments (IS/OS) was not detected in all eyes with retinal detachment (RD). However, IS/OS became visible after resolution of serous RD in 51 eyes (81.0%). SD-OCT images at the leakage sites showed a bump of retinal pigment epithelium (RPE) in in 47 cases (68.1%) and pigment epithelial detachment (PED) in 22 of 69 leakage sites (31.9%). In 14 of 69 leakage sites (20.3%), highly reflective areas suggesting fibrinous exudate were observed in the subretinal space. In nine leakage sites (13.0%), sagging or dipping of the posterior retinal layer was seen. Abnormal RPE changes such as RPE bump and PED were observed in 12 of 22 fellow eyes (54.5%). CONCLUSIONS: A variety of morphologic changes could be identified on SD-OCT, and those findings may contribute more information to our understanding of the pathophysiology of CSC.
