A Comparative Study on Transcatheter Renal Arterial Embolization (TRAE) in Rabbits with Absolute Ethanol and Gelfoam Particles.
10.3348/jkrs.1996.34.4.473
- Author:
Tae Hoon KIM
1
;
Pil Mun YU
;
Young Hee CHOI
;
Sang Joon KIM
;
Yeon Hee LEE
;
Seung Cheol KIM
;
Pil Won SUH
;
Na Hye MYUNG
;
Sung Chul YOON
Author Information
1. Department of Radiology, Dan Kook University Hospital, Korea.
- Publication Type:Comparative Study ; Original Article
- Keywords:
Kidney, interventional procedure;
Kidney, angiography;
Arteries, therapeutic blockade
- MeSH:
Angiography;
Arteries;
Ethanol*;
Gelatin Sponge, Absorbable;
Kidney;
Pathology;
Rabbits*;
Renal Artery
- From:Journal of the Korean Radiological Society
1996;34(4):473-480
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To evaluate the therapeutic effectiveness of absolute ethanol and gelfoam particles and the degree of vascular recanalization after gelfoam embolization. MATERIALS AND METHODS: Transcatheter renal arterial embolization(TRAE) was performal in 16 rabbits ; Eight were embolized with absolute ethanol, and eight with gelfoam particles. Of this total, three died less than one week after embolization. Pre- and post embolization angiographies at five minutes, one week, two weeks(gelfoam group only) and 5-6 weeks after embolization were performed. Six rabbits were sacrificed at one week, and seven at 5-6 weeks after embolization. Pathologic examination was performed. RESULTS: The ethanol group(n=6) showed complete occlusion of the main renal artery on follow-up angiography at one week and 5-6 weeks after embolization. The pathologic finding was complete total necrosis of embolized kidneys. The gelfoam group(n=7) showed partial recanalization of renal arteries in follow upangiography at one week, two weeks and 5-6 weeks after embolization. The pathologic finding was partial lysis ofgelfoam particles within intrarenal arteries. CONCLUSION: Absolute ethanol can be used as a permanent embolicagent and gelfoam as a temporary such agent in various clinical applications. Gelfoam, however, did not show complete recanalization on angiography and pathology at six weeks after embolization.
