A Case of Nicolau Syndrome.
- Author:
Seung Yong LEE
1
;
Seong Hyun PARK
;
Ji Hyun YI
;
Jin Seok HONG
;
Seok Kweon YUN
;
Han Uk KIM
;
Chull Wan IHM
Author Information
1. Department of Dermatology, Chonbuk National University Medical School, Jeonju, Korea. dermayun@chonbuk.ac.kr
- Publication Type:Case Report
- Keywords:
Diclofenac-beta-dimethyl-aminoethanol;
Nicolau syndrome
- MeSH:
Buttocks;
Exanthema;
Female;
Humans;
Injections, Intramuscular;
Middle Aged;
Necrosis;
Skin
- From:Korean Journal of Dermatology
2006;44(11):1380-1382
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Nicolau syndrome is a rare adverse reaction of the skin at the site of intramuscular drug injection, and has largely unidentified pathogenesis. It consists of the development of an acute, severe pain and a localized erythematous rash during intramuscular injection leading to cutaneous, subcutaneous and even muscular necrosis. We report a case of a 55-year-old woman who presented with a painful skin necrosis in her buttocks following an intramuscular diclofenac-beta-dimethyl-aminoethanol injection.