Pharmacologic Treatment Strategies of Type 2 Diabetes.
- Author:
Youhern AHN
1
Author Information
1. Department of Internal Medicine, School of Medicine, Hanyang University, Seoul, Korea. ahnyh@hanyang.ac.kr
- Publication Type:Original Article
- Keywords:
Intensive diabetes therapy;
Cardiovascular disease;
Comprehensive approach
- MeSH:
Cardiovascular Diseases;
Heart Diseases;
Humans;
Motor Activity;
Obesity;
Prevalence;
Risk Factors
- From:Hanyang Medical Reviews
2009;29(2):148-167
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Type 2 diabetes has become epidemic in the past several decades owing to advancing age, a substantially increased prevalence of obesity and decreased physical activities etc. Achieving & maintaning glycemic level as close to the nondiabetic range as possible through intensive diabetes therapy has been demonstrated to have a powerful beneficial effect on diabetesspecific microvascular complications in type 1 & type 2 diabetes. However, diabetes is associated with a reduced lifespan, largely as a consequence of cardiovascular disease. Unlike type 1 diabetes, current studies have failed to demonstrate a beneficial effect of intensive diabetes therapy on cardiovascular disease in type 2 diabetes. Accordingly, special consideration may now need to be given to high-risk patients with multiple risk factors & heart disease. Therefore, comprehensive approach to the treatment of type 2 diabetes that include the treatment of all of the coexisting risk factors for cardiovascular disease has to be implemented and achieved