A Case of Cytomegalovirus Colitis with Endoscopic Finding Resembling Crohn's Disease.
10.4166/kjg.2012.59.4.303
- Author:
Cheal Wung HUH
1
;
Young Hoon YOUN
;
Da Hyun JUNG
;
Do Whan KIM
;
Bo Gun KHO
;
Jie Hyun KIM
;
Hyojin PARK
;
Sang In LEE
Author Information
1. Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea. DRYOUN@yuhs.ac
- Publication Type:Case Reports ; English Abstract
- Keywords:
Cytomegalovirus colitis;
Longitudinal ulcer;
Crohn's disease
- MeSH:
Aged, 80 and over;
Antiviral Agents/therapeutic use;
Colitis/*diagnosis/etiology/pathology;
Colonoscopy;
Crohn Disease/diagnosis;
Cytomegalovirus Infections/*diagnosis/drug therapy/pathology;
Ganciclovir/therapeutic use;
Humans;
Immunohistochemistry;
Injections, Intravenous;
Male;
Tomography, X-Ray Computed
- From:The Korean Journal of Gastroenterology
2012;59(4):303-307
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Cytomegalovirus (CMV) colitis is common among immunocompromised patients, and often diagnosed by pathologic confirmation because it is associated with a diverse spectrum of clinical and endoscopic features. However, Crohn's disease has no definitive diagnostic criteria, but longitudinal ulcers and cobble stone appearance are accepted as typical endoscopic features of Crohn's disease. An 83 year-old male with a history of radiotherapy for hypopharyngeal cancer visited our hospital with a complaint of melena for 1 week. His colonoscopic exam showed multiple longitudinal ulcers along the entire colon. Most of the ulcers were longer than 4 cm, these endoscopic findings were suspected as typical endoscopic features of Crohn's disease. Pathologic reports revealed multiple inclusion bodies with CMV on immunohistochemistry. He was finally diagnosed as having CMV colitis, and received a 3 week-course of intravenous ganciclovir. A colonoscopic follow-up showed complete healing of the multiple longitudinal ulcers, and he is doing well now without further treatment.
