A Case of Type III Hyperlipoproteinemia Associate with Xanthoma Tuberosum and Xanthoma Striatum Palmare.
- Author:
Nam Joon CHO
;
Wook LEW
;
Jeong Ho KIM
;
Seung Hun LEE
- Publication Type:Case Report
- MeSH:
Adult;
Buttocks;
Chemistry;
Cholesterol;
Cholesterol, VLDL;
Diet;
Elbow;
Electrophoresis;
Gemfibrozil;
Humans;
Hyperlipoproteinemia Type III*;
Lipoproteins;
Male;
Plasma;
Reference Values;
Skin;
Triglycerides;
Ultracentrifugation;
Xanthomatosis*
- From:Korean Journal of Dermatology
1994;32(2):321-326
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We report a case of type III hyperlipoproteinemia associated with xanthoma eruptivum. Xanthoma tuberosum, and xanthoma striatum palmare whose clinical symptoms have been improved by the treatment of gemfibrozil. A 31-year-old male patient visited our clinic for evaluation of multiple yellowish nodules on the elbows, multiple yellowish plaques on the buttocks and linear yellowish plaques along with the palmar creases on both palms. The blood chemistry showed an elevation of cholesterol and triglyceride. Lipoprotein electrophoresis showed broad betazone and plasma standing test showed turbid plasma. Lipoprotein ultracentrifugation showed that the ratio of VLDL cholesterol and plasma triglyceride was 0.38. According to the above findings, we diagnosed this patient as type III hyperlipoproteinemia. After 4 months of treatment with diet and gemfibrozil, the serum level of cholesterol and triglyceride were reduced to normal range. The skin lesions of both palms showed marked improvement but the skin lesions on elbows and buttocks were not much improved.
