A Case of Acromegaly Associated with Lung and Gastric Cancer.
10.4046/trd.2005.59.2.198
- Author:
Jin Soo KIM
1
;
Uk Hyun KIL
;
Do Seon SONG
;
Hong Jun YANG
;
Hyeug LEE
;
Min HUH
;
Jeong Pyo KIM
;
Soon Seog KWON
;
Young Kyoon KIM
;
Kwan Hyoung KIM
;
Hwa Sik MOON
;
Jeong Sup SONG
;
Sung Hak PARK
;
Joong Hyun AHN
Author Information
1. Department of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea. ajhcmcim@olmh.co.kr
- Publication Type:Case Report
- Keywords:
Acromegaly;
Lung cancer;
Gastric cancer
- MeSH:
Acromegaly*;
Growth Hormone;
Humans;
Incidence;
Insulin;
Insulin-Like Growth Factor I;
Lung Neoplasms;
Lung*;
Middle Aged;
Mortality;
Stomach Neoplasms*
- From:Tuberculosis and Respiratory Diseases
2005;59(2):198-203
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Patients with acromegaly have high incidence of benign or malignant neoplasia than general population. Around fifteen percent of the deaths reported in acromegaly are attributable to malignancy of cancer. On the whole, mortality in acromegaly has been shown to be correlated with the degree of growth hormone (GH) control. Especially, the levels of insulin like growth factor-1 (IGF-1) may be higher in neoplasm, but there is no clear evidence to prove that tumor development is triggered by IGF-1 in acromegaly. Henceforth, we report a case of acromegaly associated with lung and gastric cancer in a 58-year-old man, suggesting the possible carcinogenic role of IGF-1.
