Effect of Excimer Laser Photorefractive Keratectomy on Density and Morphology of Corneal Endothelial Cells.
- Author:
Won Ryang WEE
1
;
Kayoung YI
;
Myung Hee LEE
;
Jin Ho CHANG
;
Jin Hak LEE
Author Information
1. Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Excimer laser photorefractive keratectomy;
Corneal endothelium;
Contact lens
- MeSH:
Contact Lenses;
Endothelial Cells*;
Endothelium, Corneal;
Humans;
Lasers, Excimer*;
Microscopy;
Photorefractive Keratectomy*;
Seoul
- From:Journal of the Korean Ophthalmological Society
1998;39(1):37-41
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We investigated the effect of excimer laser photorefractive keratectomy (PRK) on corneal endothelium in both contact lens wearer and non-wearer. Myopes (-3.0D~-9.5D) who underwent excimer laser PRK at Seoul National University Hospital from March to September 1996 were enrolled in this study. Six patients of 9 eyes had no history of contact lens wearing or discontinued wearing contact lens at least 1 year preoperatively (contact lens non-wearers) and 10 patients of 17 eyes wore their contact lenses until 4 weeks before surgery (contact lens wearers). The cnetral corneal endothelial cell density and morphology were evaluated by specular microscopy before and 1week, 3 and 6 months after surgery. In contact lens non-wearer group, no significant postoperative change was observed. But in contact lens wearer group, significnat increase of density and significant decrease fo pleopmorphism index were noted at postoperative 3 and 6 months, respectively. These results suggest that excimer laser PRK does not affect central corneal endothelium and the discontinuation of wearing contact lens may induce postoperative change of corneal endothelim.
