Risk Factors for Cryptorchidism.
- Author:
Jun Mo KIM
1
;
Nam Kyu LEE
;
Young Ho PARK
Author Information
1. Department of Urology, Soonchunhyang University College of Medicine, Chonan and Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Cryptorchidism;
Risk factor;
Low birth weight;
Congenital anomalies
- MeSH:
Abortion, Induced;
Apgar Score;
Birth Weight;
Chungcheongnam-do;
Cryptorchidism*;
Female;
Gestational Age;
Humans;
Infant, Low Birth Weight;
Infant, Newborn;
Logistic Models;
Male;
Maternal Age;
Odds Ratio;
Parity;
Parturition;
Paternal Age;
Pre-Eclampsia;
Pregnancy;
Pregnancy Trimester, Third;
Risk Factors*;
Scrotum;
Testis;
Twins
- From:Korean Journal of Urology
2001;42(6):627-630
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: The testes normally descend into the scrotum during last trimester in ges tation. Although the cause of maldesent is not clear, abnormality of the gubernaculum testis, intrinsic testicular defect and deficient gonadotropic stimulation are considered as possible etiology. We evaluated risk factors for cryptorchidism, including low birth weight, low gestational age, twin birth and other pertinent factors. MATERIALS AND METHODS: 2,605 boys who were born in Soonchunhyang Chonan hospital between March 1997 and March 2000 were evaluated for cryptorchidism. The subjects consisted with 99 boys with cryptorchidism and 2,506 normal boys for control group. We investigated birth weight, duration of gestation, twin birth, parity, other congenital anomalies, paternal age, maternal age, previous abortion history, mode of delivery (normal vaginal delivery or Cesarean section), Apgar score (1 minute), breech presen tation and preeclampsia during pregnancy to each subject in both groups. Statistical analysis was performed using logistic regression analysis to estimate the odds ratio. RESULTS: The birth weight less than 1,500gm and other congenital anomalies were significant risk factors for crytorchidism. The other factors showed no effect on the risk of cryptorchidism. CONCLUSIONS: This study shows that low birth weight and other congenital anomalies are the significant risk factors for development of cryptorchidism.