Analysis of para-chloroaniline after chemical interaction between alexidine and sodium hypochlorite using mass spectrometry: A preliminary study.
10.5395/JKACD.2010.35.4.295
- Author:
Hyeon Sik KIM
1
;
Seung Hyun HAN
;
Soram OH
;
Sang Min LIM
;
Yu GU
;
Kee Yeon KUM
Author Information
1. Department of Conservative Dentistry, School of Dentistry, Seoul National University, Seoul, Korea. kum6139@snu.ac.kr
- Publication Type:Original Article
- Keywords:
Alexidine;
Chemical interaction;
Mass spectrometry;
Para-chloroaniline;
Sodium hypochlorite
- MeSH:
Aniline Compounds;
Biguanides;
Dental Pulp Cavity;
Eye;
Mass Spectrometry;
Passive Cutaneous Anaphylaxis;
Sodium;
Sodium Hypochlorite;
Spectrum Analysis
- From:Journal of Korean Academy of Conservative Dentistry
2010;35(4):295-301
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The purposes of this study were firstly to investigate the any formation of precipitate after interaction between ALX and NaOCL and secondarily to analyze the PCA formation by using time of flight secondary ion mass (TOF-SIM) spectrometry. Mass spectrometry analysis was performed for the mixture of 0.5% ALX and 5.25% NaOCl. As controls, 2.5% CHX with 5.25% NaOCl and 1% PCA solutions were used. Any formation of precipitates in 10 tested solutions was evaluated by naked eye. Results of mass spectrum showed that the typical peak of PCA was not detected in mixed solution of ALX and NaOCl, whereas CHX/NaOCl mixture showed the same peak that found in the PCA spectrum. Precipitate formation was only observed in CHX/NaOCL mixture. The present TOF-SIM spectrometry results indicated that ALX can be a useful root canal irrigant combined with NaOCl during canal instrumentation. Further study is necessary to confirm the antimicrobial effect of ALX against endodontic pathogen before its clinical application as an endodontic irrigant.
