Alcoholic Peripheral Neuropathy.
- Author:
Sang Kun LEE
1
;
Seong Ho PARK
;
Duk Lyul NA
;
Sang Soo LEE
;
Kwang Woo LEE
;
Sang Bok LEE
;
Ho Jin MYUNG
;
Sung Hye PARK
;
Je Geun CHI
Author Information
1. Department of Neurology, Seoul National University, Korea.
- Publication Type:Original Article
- MeSH:
Alcoholics*;
Axons;
Biopsy;
Dermatitis;
Humans;
Knee;
Microscopy, Electron;
Myelin Sheath;
Neural Conduction;
Pellagra;
Peripheral Nervous System Diseases*;
Sensation;
Sural Nerve;
Wernicke Encephalopathy
- From:Journal of the Korean Neurological Association
1991;9(3):323-331
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Nerve conduction studies and sural nerve biopsies were performed on 13 patients with alcoholic peripheral neuropathy. Most patients had sensory loss and tingling sensation below knees. Wernicke's encephalopathy and pellagra dermatitis were commonly associated. There was no evidence of demyelinating newcpathy in nerve conductoion studies. Myelinated fiber oounts showed loss of small and largetbers in all patients, retaining a bimodal distribution. Segmental denyelination was not found in all teased fibers. Electron microscopy confirmed axonal degeneration of myelinated andunmyelinated fibers with seconday myelin change.
