Six-years' Experience of Pseudomosaicism and Maternal Cell Contamination in Cultured Amniocytes.
- Author:
Shin Yong MOON
1
;
Byung Chul JEE
;
Seok Hyun KIM
;
Sun Kyung OH
;
Joong Shin PARK
;
Young Min CHOI
Author Information
1. Department of Obstetrics and Gynecology, College of Medicine, Seoul National University, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Pseudomosaicism;
Maternal cell contamination;
Percutaneous umbilical blood sampling;
Genetic amniocentesis
- MeSH:
Amniocentesis;
Cordocentesis;
Cytogenetics;
Fetal Blood;
Mosaicism
- From:Journal of Genetic Medicine
1999;3(1):25-28
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE : To present our experiences in pseudomosaicism or maternal celi contamination in genetic mid-trimester amniocentesis confirmed through percuraneous umbilical blood sampling. METHODS : From 1992 to 1997, repeated cytogenetic evaluation with fetal cord blood was carried out in 14 cases showing mosaic patterns. RESULTS : We confirmed pseudomosaicsm in 12 cases (85.7%) by repeated cytohenetic evaluation, and also maternal cell contamination in 2 cases. CONCLUSIONS : Repeated cytohenetic evaluation via percutaneous umbilical blood sampling was a rapid and useful method fof the confirmation of mosaicism resulted from genetic mid-trimester amnicentesis.
