Comparison of the Clinical Features of Apical Hypertrophic Cardiomyopathy Versus Asymmetric Septal Hypertrophy in Korea.
10.3904/kjim.2005.20.2.111
- Author:
Hyun Suk YANG
1
;
Jae Kwan SONG
;
Jong Min SONG
;
Duk Hyun KANG
;
Cheol Whan LEE
;
Myeong Ki HONG
;
Jae Joong KIM
;
Seong Wook PARK
;
Seung Jung PARK
Author Information
1. Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. jksong@amc.seoul.kr
- Publication Type:Original Article ; Comparative Study
- Keywords:
Hypertrophic cardiomyopathy;
Prognosis;
Echocardiography
- MeSH:
Cardiomyopathy, Hypertrophic/epidemiology/*ultrasonography;
Comparative Study;
Echocardiography;
Female;
Follow-Up Studies;
*Heart Septum/ultrasonography;
*Heart Ventricles/ultrasonography;
Humans;
Korea/epidemiology;
Male;
Middle Aged;
Prevalence;
Retrospective Studies
- From:The Korean Journal of Internal Medicine
2005;20(2):111-115
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: We sought to test whether patients with apical hypertrophic cardiomyopathy (APH) have different clinical features compared to those with typical asymmetric septal hypertrophy (ASH). METHODS: Among 32, 534 patients who underwent routine echocardiography at Asan Medical Center from January 2000 to December 2001, 305 patients (0.9%), who were finally diagnosed with hypertrophic cardiomyopathy (HCMP), were evaluated. The type of HCMP was classified according to the echocardiographic findings. RESULTS: ASH was the most frequent type (n=160, 53%, group I), and APH was the second most frequent (n=91, 30%, group II). Mean age (60.8 +/- 10 vs. 48.2 +/- 14 years, p< 0.001) and prevalence of hypertension (32% vs. 19%, p=0.022) were significantly higher in group II than in group I. Family history of HCMP (4.4% vs. 0% p=0.043) and sudden cardiac death (8.8% vs. 1.1% p=0.014) was more prevalent in group I. During the follow-up period of 32.0 +/- 37.2 months, cardiac events occurred at a significantly higher rate in group I (25.5% vs. 8.8%, p=0.003). CONCLUSION: APH comprises a significant proportion of HCMP in Korea and patients with APH show different clinical features compared to those with ASH.
