A Case of Acute Lymphoblastic Leukemia with dic(9;12) and Additional Trisomy 8.
- Author:
Duck CHO
1
;
Seung Jin YANG
;
Je Jung LEE
;
Hyeoung Joon KIM
;
Dong Wook RYANG
Author Information
1. Department of Laboratory Medicine,Chonnam National University Medical School, Gwangju, Korea. ryang@hitel.net
- Publication Type:Case Report
- Keywords:
Acute lymphoblastic leukemia;
Dic(9;
12)
- MeSH:
Adolescent;
Bone Marrow;
HLA-DR Antigens;
Humans;
Immunophenotyping;
Induction Chemotherapy;
Lymphatic Diseases;
Male;
Physical Examination;
Platelet Count;
Precursor Cell Lymphoblastic Leukemia-Lymphoma*;
Splenomegaly;
Trisomy*
- From:The Korean Journal of Laboratory Medicine
2002;22(4):220-223
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A 16-year-old boy was diagnosed with acute lymphoblastic leukemia with dic(9;12). Physical examination revealed cervical lymphadenopathy and splenomegaly. Hemoglobin was 5.1 g/dL, WBC was 4,400/microL and the platelet count was 3,000/ L. Immunophenotyping showed positivity of HLA-DR, CD34, CD10, CD19, CD20, and CD22. The chromosome analysis of bone marrow aspirate showed 46,XY,+8,dic(9;12)(p11-13;p11-12). There has been a complete remission by induction chemotherapy as of the 62nd day.
