Clinicopathologic Characteristics and Treatment Outcomes of Penile Cancer.
10.5534/wjmh.2017.35.1.28
- Author:
Jong Kil NAM
1
;
Dong Hoon LEE
;
Sung Woo PARK
;
Sung Chul KAM
;
Ki Soo LEE
;
Tae Hyo KIM
;
Taek Sang KIM
;
Cheol Kyu OH
;
Hyun Jun PARK
;
Tae Nam KIM
Author Information
1. Department of Urology, Pusan National University Yangsan Hospital, Yangsan, Korea. toughkil76@naver.com
- Publication Type:Original Article
- Keywords:
Penile neoplasms;
Prognosis;
Treatment outcome
- MeSH:
Biopsy;
Carcinoma, Squamous Cell;
Drug Therapy;
Follow-Up Studies;
Humans;
Joints;
Male;
Medical Records;
Multivariate Analysis;
Pathology;
Penile Neoplasms*;
Prognosis;
Radiotherapy;
Treatment Outcome
- From:The World Journal of Men's Health
2017;35(1):28-33
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: The aim of this study was to assess the clinicopathologic characteristics of penile cancer, including patterns of therapy, oncologic results, and survival. MATERIALS AND METHODS: Between January 2005 and July 2015, 71 patients at 6 institutions who had undergone penectomy or penile biopsy were enrolled. Their medical records were reviewed to identify the mode of therapy, pathology reports, and cancer-specific survival (CSS) rate. RESULTS: Clinicopathologic and outcome information was available for 52 male patients (mean age, 64.3 years; mean follow-up, 61.4 months). At presentation, 17 patients were node-positive, and 4 had metastatic disease. Management was partial penectomy in 34 patients, total penectomy in 12 patients, and chemotherapy or radiotherapy in 6 patients. The pathology reports were squamous cell carcinoma in 50 patients and other types of carcinoma in the remaining 2 patients. Kaplan-Meier survival analysis showed a 5-year CSS rate of 84.0%. In univariate and multivariate analyses, the American Joint Committee on Cancer (AJCC) stage and pathologic grade were associated with survival. CONCLUSIONS: Partial penectomy was the most common treatment of penile lesions. The oncologic outcomes were good, with a 5-year CSS of 84.0%. The AJCC stage and pathologic grade were independent prognostic factors for survival.
