Hypernatremia-Induced Rhabdomyolysis in a Patient with Meningioma Involving the Pituitary Gland.
10.3904/kjm.2015.88.3.324
- Author:
Hye Won LEE
1
;
Jong Min YUN
;
Joo Yeun HU
;
Ji Eun KIM
;
Young Joo KIM
;
Kyung Jin SEO
;
Young Ok KIM
Author Information
1. Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea. cmckyo@catholic.ac.kr
- Publication Type:Case Report
- Keywords:
Rhabdomyolysis;
Hypernatremia;
Diabetes insipidus;
Pituitary gland
- MeSH:
Biopsy;
Brain;
Creatine Kinase;
Deamino Arginine Vasopressin;
Diabetes Insipidus;
Diagnosis;
Humans;
Hypernatremia;
Magnetic Resonance Imaging;
Male;
Meningioma*;
Middle Aged;
Pituitary Gland*;
Polyuria;
Radionuclide Imaging;
Rhabdomyolysis*;
Sodium
- From:Korean Journal of Medicine
2015;88(3):324-329
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Hypernatremia is a rare cause of rhabdomyolysis. Here, we report a case of hypernatremia-induced rhabdomyolysis in a patient with meningioma involving the pituitary gland. A 61-year-old male was admitted for decreased mentality and poor oral intake. He had undergone an operation for meningioma 10 years prior. At admission, he appeared lethargic and severely dehydrated with an initial sodium level of 178 mEq/L. Hypernatremia remained persistent despite massive hydration and the serum creatine phosphokinase level was 18,047 U/L after 3 days. Bone scintigraphy also showed findings consistent with rhabdomyolysis. Brain magnetic resonance imaging revealed extensive masses involving the pituitary gland and an intranasal biopsy confirmed meningioma. Polyuria, and low anti-diuretic hormone levels supported the diagnosis of central diabetes insipidus-induced hypernatremia. Desmopressin was administered intranasally and the patient's serum sodium and muscle enzyme levels were normalized.
