PM10 Exposure and Non-accidental Mortality in Asian Populations: A Meta-analysis of Time-series and Case-crossover Studies.
- Author:
Hye Yin PARK
1
;
Sanghyuk BAE
;
Yun Chul HONG
Author Information
1. Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea. ychong1@snu.ac.kr
- Publication Type:Original Article ; Meta-Analysis
- Keywords:
PM10;
Non-accidental mortality;
Asia;
Meta-analysis
- MeSH:
Air Pollutants/*chemistry;
Asian Continental Ancestry Group;
Cross-Over Studies;
Databases, Factual;
*Environmental Exposure;
Humans;
Models, Theoretical;
*Mortality;
Particulate Matter/*chemistry;
Time Factors
- From:Journal of Preventive Medicine and Public Health
2013;46(1):10-18
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVES: We investigated the association between particulate matter less than 10 microm in aerodynamic diameter (PM10) exposure and non-accidental mortality in Asian populations by meta-analysis, using both time-series and case-crossover analysis. METHODS: Among the 819 published studies searched from PubMed and EMBASE using key words related to PM10 exposure and non-accidental mortality in Asian countries, 8 time-series and 4 case-crossover studies were selected for meta-analysis after exclusion by selection criteria. We obtained the relative risk (RR) and 95% confidence intervals (CI) of non-accidental mortality per 10 microg/m3 increase of daily PM10 from each study. We used Q statistics to test the heterogeneity of the results among the different studies and evaluated for publication bias using Begg funnel plot and Egger test. RESULTS: Testing for heterogeneity showed significance (p<0.001); thus, we applied a random-effects model. RR (95% CI) per 10 microg/m3 increase of daily PM10 for both the time-series and case-crossover studies combined, time-series studies relative risk only, and case-crossover studies only, were 1.0047 (1.0033 to 1.0062), 1.0057 (1.0029 to 1.0086), and 1.0027 (1.0010 to 1.0043), respectively. The non-significant Egger test suggested that this analysis was not likely to have a publication bias. CONCLUSIONS: We found a significant positive association between PM10 exposure and non-accidental mortality among Asian populations. Continued investigations are encouraged to contribute to the health impact assessment and public health management of air pollution in Asian countries.
