A Case of Balsalazide-Induced Limited Form of Granulomatosis with Polyangiitis with Bronchiolitis Obliterans Organizing Pneumonia-like Variant in Ulcerative Colitis.
10.4046/trd.2012.72.3.323
- Author:
Shin Myung KANG
1
;
Young Rock JANG
;
Hyun Hwa YOON
;
Suji KIM
;
Eun Young KIM
;
Seung Yeon HA
;
Jeong Woong PARK
Author Information
1. Department of Pulmonary and Critical Care Medicine, Gachon University Gil Hospital, Incheon, Korea. jwpark@gilhospital.com
- Publication Type:Case Report
- Keywords:
Balsalazide;
Wegener Granulomatosis;
Colitis, Ulcerative
- MeSH:
Bronchiolitis;
Bronchiolitis Obliterans;
Colitis, Ulcerative;
Humans;
Mesalamine;
Multiple Pulmonary Nodules;
Phenylhydrazines;
Thorax;
Ulcer;
Wegener Granulomatosis
- From:Tuberculosis and Respiratory Diseases
2012;72(3):323-327
- CountryRepublic of Korea
- Language:English
-
Abstract:
5-Aminosalicylate agents are the main therapeutic agents for ulcerative colitis. Balsalazide is a prodrug of 5-aminosalicylate and has fewer side effects than the other 5-aminosalicylate agents. Pulmonary complications resembling granulomatosis with polyangiitis in ulcerative colitis are extremely rare. Here, we report a patient with ulcerative colitis on balsalazide presenting respiratory symptoms and multiple pulmonary nodules from a chest radiography that was pathologically diagnosed with a limited form of granulomatosis with polyangiitis with bronchiolitis obliterans organizing pneumonia-like variant. To our knowledge, this is the first report of a balsalazide-induced limited form of granulomatosis with polyangiitis with bronchiolitis obliterans organizing pneumonia-like variant.
