Infection Rate of Chlamydia pneumoniae in Patients with Chronic Cough.
10.4046/trd.2010.69.6.426
- Author:
Seung Yeon CHUN
1
;
Kwon Oh PARK
;
Yong Bum PARK
;
Jeong Hee CHOI
;
Jae Young LEE
;
Eun Kyung MO
;
Sung Hoon PARK
;
Cheol Hong KIM
;
Chang Youl LEE
;
Yong Il HWANG
;
Seung Hun JANG
;
Tae Rim SHIN
;
Sang Myeon PARK
;
Dong Gyu KIM
;
Myung Goo LEE
;
In Gyu HYUN
;
Ki Suck JUNG
Author Information
1. Department of Internal Medicine, Hallym University College of Medicine, Chuncheon, Korea. bfspark@medimail.co.kr
- Publication Type:Original Article
- Keywords:
Cough;
Polymerase Chain Reaction;
Chlamydia Infections
- MeSH:
Adult;
Allergens;
Asthma;
Bronchitis;
Chlamydia;
Chlamydia Infections;
Chlamydophila pneumoniae;
Cough;
Eosinophils;
Heart;
Humans;
Methacholine Chloride;
Paranasal Sinuses;
Pneumonia;
Polymerase Chain Reaction;
Skin;
Sputum;
Thorax
- From:Tuberculosis and Respiratory Diseases
2010;69(6):426-433
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Persistent cough has recently been found to be associated with Chlamydia pneumoniae infection. We aimed to investigate the infection rate of C. pneumonia in adult patients with chronic cough. METHODS: We recruited 68 patients with persistent cough lasting in excess of 3 weeks, who visited Kangdong Sacred Heart Hospital from January 2005 to August 2005. On the first visit, chest and paranasal sinuses radiography, skin prick test of common allergens, and induced sputum samples for C. pneumoniae were performed in all of patients. Further evaluation for diagnosis included a methacholine provocation test and eosinophil counts in induced sputum. RESULTS: The most common cause of chronic cough was upper airway cough syndrome (UACS) (26.5%), followed by eosinophilic bronchitis (20.6%) and cough variant asthma (16.2%). Idiopathic chronic cough was the cause in 33.8% of patients. The mean duration of cough was 11.7 months. C. pneumoniae was isolated by polymerase chain reaction (PCR) from one patient who had upper respiratory air way syndrome. CONCLUSION: Chlamydia pneumoniae appears to have a minor role as a cause of chronic cough in patients.
