Incidence and clinical course of HELLP syndrome in pregnant women.
- Author:
Jae Wook KIM
1
;
Tae Chul PARK
;
Jin Woo LEE
;
Jae Cheol KWON
;
Yoo Na KANG
;
Sook Hee HONG
;
Young Soo KIM
;
Sun Ae YOON
;
Young Ok KIM
Author Information
1. Department of Internal Medicine, Bundang Jesaeng General Hospital, Seongnam, Korea.
- Publication Type:Original Article
- Keywords:
Pregnancy;
HELLP syndrome;
Preeclampsia;
Pregnancy complications
- MeSH:
Acute Kidney Injury;
Aspartate Aminotransferases;
Female;
Fetal Death;
Fetal Growth Retardation;
HELLP Syndrome*;
Hemolysis;
Hemorrhage;
Humans;
Hypertension;
Incidence*;
Korea;
Liver;
Maternal Death;
Platelet Count;
Postpartum Period;
Pre-Eclampsia;
Pregnancy;
Pregnancy Complications;
Pregnant Women*;
Pulmonary Edema;
Renal Insufficiency;
Retrospective Studies
- From:Korean Journal of Medicine
2004;67(5):521-527
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Although HELLP syndrome (hemolysis, elevated liver enzymes, low platelets) is a serious medical complications including coagulopathy, hypertension, hepatic and renal failures, and pulmonary edema in pregnant women, the data about HELLP syndrome were rarely reported in the medical journal in Korea. METHODS: Nineteen cases of HELLP syndrome were retrospectively studied out of 16,910 pregnant women from January 1998 to March 2004 at Uijongbu St. Mary's Hospital. We analyzed incidence, clinical symptoms, laboratory findings, maternal and clinical complications and clinical course of HELLP syndrome. RESULTS: The incidence of HELLP syndrome was 0.27% (19/16,910) in total pregnant women and 4.15% (19/458) in women with preeclampsia. All patients had evidence of hemolysis and serum aspartate aminotransferase level >or= 70 IU/L, and platelet counts
