Two Cases of Discontinuation Syndrome Following Cessation of Cholinesterase Inhibitors.
- Author:
Yong Tae KWAK
1
Author Information
1. Department of Neurology, Yong-in Hyoja Geriatric Hospital, Yongin, Korea. ytkwak@drkwak.com
- Publication Type:Case Report
- Keywords:
Discontinuation syndrome;
Cholinesterase inhibitor;
Alzheimer's disease
- MeSH:
Alzheimer Disease;
Cholinesterase Inhibitors*;
Cholinesterases*;
Humans
- From:Journal of the Korean Neurological Association
2004;22(4):386-388
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Discontinuation syndrome is a cluster of symptoms that appear when a patient terminates long-term medication. We report 2 patients with Alzheimer's disease who developed significant behavioral disturbances after the cessation of cholinesterase inhibitors. Although the clinical profile of discontinuation syndrome in cholinesterase inhibitors are yet poorly defined, it may be of importance to consider this syndrome when patients develop significant behavioral disturbances after these agents are stopped, and if more severe reactions are expected, retrial of these agents may be prudent.
