Calcium Polystyrene Sulfonate Induced Colonic Necrosis in Patient with Chronic Kidney Disease.
10.4166/kjg.2010.55.4.261
- Author:
Sung Hoa LEE
1
;
Sung Jung KIM
;
Go Eun KIM
;
Woo Jin LEE
;
Won Ki HONG
;
Gwang Ho BAIK
;
Young Hee CHOI
;
Dong Joon KIM
Author Information
1. Department of Internal Medicine, Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon, Korea. ksjungdr@hallym.or.kr
- Publication Type:Case Report ; English Abstract
- Keywords:
Calcium polystyrene sulfonate;
Colon;
Necrosis;
Hyperkalemia
- MeSH:
Colonic Diseases/chemically induced/complications/*pathology;
Colonoscopy;
Female;
Humans;
Kidney Failure, Chronic/complications/*diagnosis;
Middle Aged;
Necrosis;
Polystyrenes/*adverse effects
- From:The Korean Journal of Gastroenterology
2010;55(4):261-265
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A 63-year-old woman was admitted due to right upper quadrant abdominal pain. She was going through hemodialysis due to end stage renal disease and taking calcium polystyrene sulfonate orally and rectally due to hyperkalemia. Colonoscopy showed a circular ulcerative mass on the proximal ascending colon. Biopsy specimen from the mass showed inflammation and necrotic debris. It also revealed basophilic angulated crystals which were adherent to the ulcer bed and normal mucosa. These crystals were morphologically consistent with calcium polystyrene sulfonate. She was diagnosed with calcium polystyrene phosphate induced colonic necrosis and improved with conservative treatment.
