A case of acute hemolytic transfusion reaction due to anti-Di(a) antibody: A case report.
10.4097/kjae.2012.63.4.353
- Author:
Sung Ha MUN
1
;
Seung Hwan LEE
;
Min Young NO
Author Information
1. Department of Anesthesiology and Pain Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea. anesmun@hanmail.net
- Publication Type:Case Report
- Keywords:
Anti-Dia antibody;
Antibody screening test;
Hemolytic transfusion reaction
- MeSH:
Blood Group Incompatibility;
Humans;
Incidence;
Korea;
Mass Screening;
Pyridinium Compounds
- From:Korean Journal of Anesthesiology
2012;63(4):353-356
- CountryRepublic of Korea
- Language:English
-
Abstract:
Many medical institutions in Korea have recently been performing an antibody screening test as one of the essential elements of a pre-transfusion test. The Dia antigen is well known as one of the antigens with low incidence among Caucasians; however, it has been discovered with a relatively higher incidence among Mongoloid populations. The frequency of the Dia antigen among the Korean population is estimated to be 6.4-14.5%. But in Korea, a screening panel of cells from abroad without Dia positive cells has been commonly used when a patient has an unexpected antibody screening test. Here we report a case of acute hemolytic transfusion reaction due to Anti-Dia antibody. To prevent other transfusion reaction by anti-Dia antibody, addition of Dia positive cells as unexpected antibody screening test is recommended.