Acute Generalized Exanthematous Pustulosis in a 10-month-old Infant.
- Author:
Young HER
1
;
Min Seong KIL
;
Ju Hyuk PARK
;
Chul Woo KIM
;
Sang Seok KIM
Author Information
1. Department of Dermatology, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea. drkimss@naver.com
- Publication Type:Case Report
- Keywords:
Acute generalized exanthematous pustulosis;
Drug eruption;
Infant
- MeSH:
Acute Generalized Exanthematous Pustulosis;
Amoxicillin;
Child;
Drug Eruptions;
Edema;
Eosinophils;
Epidermis;
Exanthema;
Fever;
Humans;
Infant;
Neutrophils
- From:Korean Journal of Dermatology
2009;47(11):1321-1323
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Acute generalized exanthematous pustulosis (AGEP) is an uncommon aseptic pustular eruption that usually follows recent administration of oral or parenteral drugs. Characteristic AGEP features include the sudden onset of fever with widespread erythematous eruption, rapidly progressing to a fine, non-follicular, micropustular rash. The illness usually resolves spontaneously with fever and pustulation clearing within 15 days, sometimes followed by desquamation. Histopathology shows non-follicular spongiotic pustules in the epidermis filled with neutrophils, a mixed perivascular infiltrate of neutrophils and occasional eosinophils with papillary dermal edema. We describe a 10-month-old boy with AGEP secondary to exposure to amoxicillin. This is an uncommon condition in children.
