Nonimmune hydrops fetalis: clinical characteristics and prognostic factors of neonatal survival.
- Author:
Joong Yeup LEE
1
;
Yoo Kyung SOHN
;
Soon Sup SHIM
;
June Hee IM
;
Jae Yoon SHIM
;
Joong Shin PARK
;
Jong Kwan JUN
;
Bo Hyun YOON
;
Hee Chul SYN
Author Information
1. Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Nonimmune hydrops fetalis;
Prognostic factor;
Neonatal outcome;
Fetal outcome;
Intrauterine treatment
- MeSH:
Apgar Score;
Autopsy;
Echocardiography;
Female;
Fetofetal Transfusion;
Fetus;
Gestational Age;
Hydrops Fetalis*;
Incidence;
Karyotyping;
Parturition;
Perinatal Mortality;
Pleural Effusion;
Polyhydramnios;
Pregnancy;
Seoul;
Ultrasonography
- From:Korean Journal of Obstetrics and Gynecology
2002;45(12):2196-2202
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVE: We undertook this study to find out clinical characteristics and prognostic factors of neonatal survival in nonimmune hydrops fetalis (NIHF). METHODS: From Oct. 1988 to Feb. 2001, 54 cases of nonimmune hydrops fetalis diagnosed at Seoul National University Hospital (SNUH) were included in our study. The incidence and perinatal mortality were investigated. The diagnostic work-up for associated conditions (or etiology) included detailed ultrasonography, karyotyping, fetal echocardiography, infection work-up (TORCH, parvovirus), and autopsy (if fetus was dead). Among 54 cases, 20 cases of liveborns were divided into two groups. Group I survived beyond neonatal period (survived>28 days) and group II did not (expired3 (OR=21, CI 1.77, 248.1; p<0.05), and 5-min AS>3 (p<0.01). CONCLUSION: Over 3 of 1-min and 5-min AS were meaningful factors for neonatal survival in NIHF.
