Evaluation of 51Cr labelled In-vivo Crossmatching Test.
- Author:
Kap No LEE
;
Chae Seung LIM
;
Chun Soo LIM
;
Young Ki KIM
;
Gun LEE
- Publication Type:Original Article
- MeSH:
Healthy Volunteers;
Humans;
Survival Rate
- From:Korean Journal of Blood Transfusion
1995;6(1):1-8
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
For the evaluation of the 51Cr labelled in-vivo crossmatching test as a transfusion safety test, We examined the viability of the thransfused autologous and heterologous 51Cr labelled red cell at 1 hour and 24 hour in 6 normal volunteers and 4 patients whose RBC had been stored in CPDA-1 media from 1 day to 30 day. In both autologous transfusion control group(n=3) and allogeneic transfusion control group(n=3), the in-vivo RBC survival rate were more than 70% at 1 hour and 24 hour compared to that of basal 3 minute result(percent counted as 100%), and the eluted free radioisotope activity was less than 5% compared to that of whole blood. The crossmatch incompatible patient group also satisfied the safe transfusion criteria. The mean labelling efficiency which was tested in three patients was more than 95% and also satisfactory to reliable test. We concluded that in-vivo crossmatching test using 51Cr radioisotope would give us valuable informations about transfusion safety, especially in serologically incompatible patients.
