A Case of Acneiform Eruption Occurring after Injection of Cetuximab (Erbitux(R), IMC-C225).
- Author:
Yun Lim CHOI
1
;
Kwang Jun LEE
;
Hyung Seok PARK
;
Won Serk KIM
;
Joo Heung LEE
;
Jun Mo YANG
;
Eil Soo LEE
;
Dong Youn LEE
Author Information
1. Department of Dermatology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. dylee@smc.samsung.co.kr
- Publication Type:Case Report
- Keywords:
Cetuximab;
Acneiform eruption
- MeSH:
Acneiform Eruptions*;
Biopsy;
Forehead;
Humans;
Lymphocytes;
Middle Aged;
Neutrophils;
Receptor, Epidermal Growth Factor;
Rectal Neoplasms;
Skin;
Thorax;
Cetuximab
- From:Korean Journal of Dermatology
2005;43(10):1423-1425
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We report a case of acneiform skin eruption induced by cetuximab in a 58-year-old man. Cetuximab is a new anticancer agent, which acts as a selective epidermal growth factor receptor monoclonal antibody. Our patient had taken cetuximab for the treatment of metastatic rectal cancer and visited our clinic with multiple erythematous papules and pustules on the face, postauricular area and anterior chest. A skin biopsy from his forehead revealed destruction of the follicular structure and perifollicular inflammatory cellular infiltrations composed of neutrophils and lymphocytes.
