Feasibility of laparoscopic cytoreduction in patients with localized recurrent epithelial ovarian cancer.
- Author:
E Sun PAIK
1
;
Yoo Young LEE
;
Tae Joong KIM
;
Chel Hun CHOI
;
Jeong Won LEE
;
Byoung Gie KIM
;
Duk Soo BAE
Author Information
- Publication Type:Original Article ; Research Support, Non-U.S. Gov't
- Keywords: Cytoreduction Surgical Procedures; Laparoscopy; Neoplasm Recurrence, Local; Ovarian Neoplasms; Retrospective Studies
- MeSH: Adolescent; Adult; Aged; Cytoreduction Surgical Procedures/*methods; Feasibility Studies; Female; Humans; Laparoscopy/methods; Magnetic Resonance Imaging; Middle Aged; Neoplasm Recurrence, Local/diagnostic imaging/*surgery; Neoplasms, Glandular and Epithelial/diagnostic imaging/*surgery; Ovarian Neoplasms/diagnostic imaging/*surgery; Ovary/diagnostic imaging/surgery; Positron-Emission Tomography; Retrospective Studies; Tomography, X-Ray Computed; Young Adult
- From:Journal of Gynecologic Oncology 2016;27(3):e24-
- CountryRepublic of Korea
- Language:English
- Abstract: OBJECTIVE: To assess the feasibility of laparoscopic cytoreduction in patients with localized recurrent epithelial ovarian cancer (EOC) by comparing its outcomes to those of laparotomy. METHODS: We performed retrospective analysis in 79 EOC patients who had a localized single recurrent site, as demonstrated by computed tomography (CT) scan, magnetic resonance imaging, or positron emission tomography/CT scan; had no ascites; were disease-free for 12 or more months prior; and who had undergone secondary cytoreduction (laparoscopy in 31 patients, laparotomy in 48 patients) at Samsung Medical Center between 2002 and 2013. By reviewing the electronic medical records, we investigated the patients' baseline characteristics, surgical characteristics, and surgical outcomes. RESULTS: There were no statistically significant differences between laparoscopy and laparotomy patients in terms of age, body mass index, cancer antigen 125 level, tumor type, initial stage, grade, recurrence site, type of procedures used in the secondary cytoreduction, adjuvant chemotherapy, and disease-free interval from the previous treatment. With regards to surgical outcomes, reduced operating time, shorter hospital stay, and less estimated blood loss were achieved in the laparoscopy group. Complete debulking was achieved in all cases in the laparoscopy group. CONCLUSION: The laparoscopic approach is feasible without compromising morbidity and survival in selected groups of patients with recurrent EOC. The laparoscopic approach can be a possible treatment option for recurrent EOC.
