Effect of Intracameral Triamcinolone to Control Inflammation in Rabbit Eyes.
10.3341/jkos.2010.51.5.728
- Author:
Yong Jun LEE
1
;
Dong Kyu LEE
;
Kyung Seek CHOI
;
Sung Jin LEE
;
Song Hee PARK
Author Information
1. Department of Ophthalmology, Soonchunhyang University College of Medicine, Seoul, Korea. ckseek@hosp.sch.ac.kr
- Publication Type:Original Article
- Keywords:
Cataract;
Intracameral triamcinolone acetonide;
Postoperative inflammation
- MeSH:
Anterior Chamber;
Aqueous Humor;
Cataract;
Eye;
Inflammation;
Prolapse;
Rupture;
Triamcinolone;
Vitrectomy;
Vitreous Body
- From:Journal of the Korean Ophthalmological Society
2010;51(5):728-732
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To investigate the effect of intracameral triamcinolone on the control of inflammation with rupture of the posterior lens capsule during cataract surgery in rabbit eyes. METHODS: Twenty rabbit eyes were subjected to experimentally induced rupture of the posterior lens capsule and prolapse of the vitreous body into the anterior chamber. After anterior vitrectomy with and without triamcinolone, aqueous flare was measured with a laser flare meter on days 1, 3, 7, 14 and 28. RESULTS: Vitrectomized eyes with triamcinolone showed a less marked increase in postoperative aqueous flare intensity on days 14 and 28 than did those without triamcinolone (p<0.05). CONCLUSIONS: Intracameral injection of triamcinolone was beneficial for visualizing the prolapsed vitreous in the anterior chamber and for helping to control the postoperative inflammation without adverse effects.