Rheumatoid Meningitis: Neurologic Manifestation and Pathologic Findings.
- Author:
Ki Jeong LEE
1
;
Soo Hwan YIM
;
Do Whan KIM
;
Seung Woo KIM
;
Moon Kyu LEE
;
Yang Je CHO
;
Byung In LEE
;
Kyoung HEO
;
Se Hoon KIM
Author Information
1. Department of Neurology, Yonsei University College of Medicine, Seoul, Korea. kheo@yuhs.ac
- Publication Type:Case Report
- Keywords:
Meningitis;
Rheumatoid arthritis
- MeSH:
Arthritis, Rheumatoid;
Biopsy;
Brain;
Fever;
Follow-Up Studies;
Headache;
Humans;
Inflammation;
Leg;
Meningitis;
Middle Aged;
Neurologic Manifestations;
Seizures;
Seizures, Febrile;
Unconsciousness
- From:Journal of the Korean Neurological Association
2012;30(4):301-304
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Rheumatoid meningitis, one of the most severe complications of rheumatoid arthritis, presents various symptoms such as headache, confusion, loss of consciousness, seizure, fever, and focal neurological deficits. A 63-year-old man with the history of rheumatoid arthritis presented with intermittent left leg weakness, seizures and later developed fever and confusion. Brain MRI demonstrated leptomeningeal enhancement in right fronto-parietal area. Brain biopsy revealed multifocal suppurative inflammation. After aggressive immunosuppressive treatment, he had gradually recovered and the lesion was reduced on a follow-up MRI.
