The Clinical Characteristics of Subependymal Giant Cell Astrocytoma: Five Cases.
10.14791/btrt.2015.3.1.44
- Author:
Tae Young JUNG
1
;
Young Hee KIM
;
Shin JUNG
;
Hee Jo BAEK
;
Kyung Hwa LEE
Author Information
1. Department of Neurosurgery, Chonnam National University Research Institute of Medical Sciences, Chonnam National University Hwasun Hospital & Medical School, Hwasun, Korea. jung-ty@chonnam.ac.kr
- Publication Type:Case Report
- Keywords:
Astrocytoma;
Follow-up studies;
Neurosurgery;
Tuberous sclerosis
- MeSH:
Astrocytoma*;
Cerebral Ventricles;
Diagnosis;
Follow-Up Studies;
Headache;
Humans;
Neurosurgery;
Recurrence;
Seizures;
Tuberous Sclerosis
- From:Brain Tumor Research and Treatment
2015;3(1):44-47
- CountryRepublic of Korea
- Language:English
-
Abstract:
In this study, we reviewed the clinical characteristics of five cases of subependymal giant cell astrocytoma (SEGA) at our hospital between May 1997 and July 2012. The median age was 18 years old (range, 8 to 26). The clinical symptoms were presented as seizure in two patients and headache in three patients. All the tumors were located near the foramen of Monro. The median size of the tumors was 2.5 cm (range, 1.9-4.0). Two patients showed the solitary lesion, and three had subependymal nodules and cortical tubers. The median follow-up duration was 7.4 years (range, 2.0-14.3). Three patients were associated with the tuberous sclerosis complex (TSC). Four patients showed the SEGA at the first presentation and one patient experienced the 1.9 cm-sized growing mass during 7.7 years follow-up after the diagnosis of the TSC. The mass was totally removed in four patients and subtotally in one. Postoperatively, one patient took the medication for the seizure, which was controllable. The subtotally removed mass showed the recurrence postoperative 4.1 years later, and the recurred mass was stable for 4.5 years after the recurrence. The clinical follow-up study of the SEGA showed an indolent behavior before and after the surgery.
