The Novel Approach of Multiple Colon Cancer Liver Metastases Treatment.
- Author:
Chong Woo CHU
1
;
Hyung Cheol KIM
;
Cheol Wan LIM
;
Eung Jin SHIN
;
Gyu Seok CHO
;
Ki Won YU
;
Ok Pyung SONG
;
Dae Sik HONG
;
Seong Jin PARK
;
Jun Hee CHO
;
Hae Kyung LEE
;
Hee Kyung KIM
;
Kye Won KWON
;
Eun Suk KOH
Author Information
1. Department of Surgery, Soonchunhyang University Hospital, Bucheon, Korea. cwchu@schbc.ac.kr
- Publication Type:Case Report
- Keywords:
Multiple bilobar liver metastases;
Colon cancer liver metastases;
Two-stage hepatectomy;
Occlusion balloon catheter
- MeSH:
Catheters;
Colon*;
Colonic Neoplasms*;
Drug Therapy;
Hepatectomy;
Humans;
Leucovorin;
Liver*;
Mesenteric Veins;
Middle Aged;
Neoplasm Metastasis*;
Portal Vein;
Recurrence;
Sigmoid Neoplasms;
Ultrasonography
- From:Journal of the Korean Surgical Society
2005;68(2):157-162
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Multiple bilobar liver metastases (MBLM) are the main cause of low resectability in the colon cancer liver metastases. The authors experienced one case of initially non-resectable colon cancer liver metastases. He was curatively and safely treated with a two-stage hepatectomy using the new method of future remnant liver volume growing. A 54-year-old man was referred to our department with the sigmoid colon cancer combined with MBLM, which were checked in two small metastatic lesions in the left lobe and five large sized lesions in the right lobe in the computed tomogram (CT). At first, a laparoscopy-assisted anterior resection was performed. We performed the 1st stage hepatectomy 3 weeks after the colon resection. Intra-operative Ultrasonogram (US) found 9 small superficial metastatic lesions in the left lobe. All that lesions were completely removed by non-anatomical wedge resection. An occlusion balloon catheter was placed in the right portal vein through a small branch of the inferior mesenteric vein at that time. The future remnant liver volume was sufficiently increased 3 weeks after the 1st hepatectomy. A right hepatectomy was safely performed 22 days after the 1st hepatectomy. The patient had received a regional chemotherapy (interleukin2 based immuno-chemotherapy through hepatic artery) for 6 months, then has been receiving a systemic chemotherapy (biweekly Oxaliplatin, leucovorin, plus 5-fluorouracil) without any recurrence evidence.