Bone Regeneration from Adipose Stem Cells.
- Author:
Gun Il IM
1
;
Jai Sun LEE
Author Information
1. Department of Orthopaedics, Dongguk University Ilsan Hospital, Goyang, South Korea. gunil@duih.org
- Publication Type:Review
- Keywords:
Adipose tissue;
Bone regeneration;
Mesenchymal stem cell;
Osteogenesis
- MeSH:
Adipose Tissue;
Bone Regeneration;
Durapatite;
Mesenchymal Stromal Cells;
Orthopedics;
Osteogenesis;
Regeneration;
Stem Cell Research;
Stem Cells
- From:Korean Journal of Bone Metabolism
2011;18(1):1-8
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Reconstruction of large bone defect poses a great challenge to an orthopedic surgeon. Recent advancement in stem cell research ushered the treatment of bone defect with tissue-engineered bone into near-possibility. While adipose stem cells (ASCs) are the most available cell sources for tissue regeneration, their low osteogenic potential is a disadvantage. Several strategies have been developed to enhance the osteogenic differentiation of ASCs. In this review, we summarized literatures and our experience on the technology to promote osteogenesis from ASCs.
