Hepatocellular Carcinoma with Severe Hypoglycemia: Involvement of Insulin-ike Growth Factor I, II and Insulin-ike Growth Factor Binding Proteins.
- Author:
Seok Joo KIM
;
Bo Yeong YUN
;
Ha Chin CHOI
- Publication Type:Original Article
- Keywords:
Hepatocellular carcinoma;
Hypoglycemia;
IGF;
IGFBP
- MeSH:
Carcinoma, Hepatocellular*;
Carrier Proteins*;
Fibrinogen*;
Hypoglycemia*;
Insulin-Like Growth Factor Binding Proteins;
Insulin-Like Growth Factor I;
Plasma;
Reference Values;
Ultrasonography;
Venous Thrombosis
- From:The Korean Journal of Hepatology
1999;5(4):332-337
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We report a case of hepatocellular carcinoma presented with severe hypoglycemia. Computerized tomography and ultrasonography revealed a massive bilateral tumor with portal vein thrombosis. The levels of IGF-I (113 ng/mL) and IGFBP- (815 ng/mL) measured in the plasma, were lower than normal range. There was strong immunoreactivity of IGF- and IGF-I in immunohistochemical stain of tumor cells.
