Tooth Loss May Predict Poor Cognitive Function in Community-Dwelling Adults without Dementia or Stroke: The PRESENT Project.
10.3346/jkms.2013.28.10.1518
- Author:
Hyunyoung PARK
1
;
Seung Han SUK
;
Jin Sung CHEONG
;
Hak Seung LEE
;
Hyuk CHANG
;
Seung Yeon DO
;
Ji Sook KANG
Author Information
1. Department of Neurology, Wonkwang University School of Medicine, Institute of Wonkwang Clinical Medicine, Iksan, Korea. suksh@wonkwang.ac.kr
- Publication Type:Original Article ; Research Support, Non-U.S. Gov't
- Keywords:
Oral Health;
Tooth Loss;
Cognitive Impairment;
Dementia
- MeSH:
Aged;
Aged, 80 and over;
Cognition Disorders/*diagnosis/etiology;
Cohort Studies;
Dementia/pathology;
Female;
Humans;
Male;
Middle Aged;
Odds Ratio;
Periodontal Diseases/complications;
Residence Characteristics;
Stroke/pathology;
*Tooth Loss
- From:Journal of Korean Medical Science
2013;28(10):1518-1521
- CountryRepublic of Korea
- Language:English
-
Abstract:
Periodontal disease is a potential predictor of stroke and cognitive impairment. However, this association is unclear in adults aged 50 yr and above without a history of stroke or dementia. We evaluated the association between the number of teeth lost, indicating periodontal disease, and cognitive impairment in community-dwelling adults without any history of dementia or stroke. Dental examinations were performed on 438 adults older than 50 yr (315 females, mean age 63+/-7.8 yr; 123 males, mean age 61.5+/-8.5 yr) between January 2009 and December 2010. In the unadjusted analysis, odds ratios (OR) of cognitive impairment based on MMSE score were 2.46 (95% CI, 1.38-4.39) and 2.7 (95% CI, 1.57-4.64) for subjects who had lost 6-10 teeth and those who had lost more than 10 teeth, respectively, when compared with subjects who had lost 0-5 teeth. After adjusting for age, education level, hypertension, diabetes, hyperlipidemia, and smoking, the relationship remained significant (OR, 2.0; 95% CI, 1.08-3.69, P=0.027 for those with 6-10 teeth lost; OR, 2.26; 95% CI, 1.27-4.02, P=0.006 for those with more than 10 teeth lost). The number of teeth lost is correlated with cognitive impairment among community-dwelling adults aged 50 and above without any medical history of stroke or dementia.
