Improvement of Dementia Screening Accuracy of Mini-Mental State Examination by Education-Adjustment and Supplementation of Frontal Assessment Battery Performance.
10.3346/jkms.2013.28.10.1522
- Author:
Jee Wook KIM
1
;
Dong Young LEE
;
Eun Hyun SEO
;
Bo Kyung SOHN
;
Shin Young PARK
;
Il Han CHOO
;
Jong Chul YOUN
;
Jin Hyeong JHOO
;
Ki Woong KIM
;
Jong Inn WOO
Author Information
1. Department of Neuropsychiatry, Hallym University Dongtan Sacred Heart Hospital, Hwaseong, Korea.
- Publication Type:Original Article ; Research Support, Non-U.S. Gov't
- Keywords:
Mini-Mental State Examination;
Frontal Assessment Battery;
Education;
Dementia;
Screening Accuracy
- MeSH:
Aged;
Aged, 80 and over;
Alzheimer Disease/complications/diagnosis;
Area Under Curve;
Dementia/complications/*diagnosis;
Demography;
Diagnosis, Differential;
Female;
Humans;
Male;
Middle Aged;
Neuropsychological Tests;
ROC Curve
- From:Journal of Korean Medical Science
2013;28(10):1522-1528
- CountryRepublic of Korea
- Language:English
-
Abstract:
This study aimed to investigate whether the demographic variable-adjustment and supplementation of Frontal Assessment Battery (FAB) score can improve the screening ability of Mini-Mental State Examination (MMSE) for dementia and its subtypes. Five hundred forty-one non-demented comparison (NC) and 474 dementia (320 Alzheimer's disease [AD]; 139 non-Alzheimer's disease dementia [NAD]; and 15 mixed AD-NAD dementia) individuals living in the community were included. Education-adjusted MMSE (MMSE-edu) score showed significantly better screening accuracy for overall dementia, AD, and NAD than MMSE raw score. FAB-supplemented MMSE (MMSE-FAB) score had significantly better screening ability for NAD, but not for overall dementia and AD, than MMSE raw score alone. Additional supplementation of FAB to MMSE-edu further increased the ability for overall dementia or NAD screening, but not for AD screening. Further education adjustment of MMSE-FAB also improved its ability for overall dementia, AD, and NAD screening. These results strongly support the usefulness of education-adjustment and supplementation of frontal function assessment to improve screening performance of MMSE for dementia and its subtypes, NAD in particular.
