Implantable drug delivery systems with morphine in fibromyalgia: A case report.
10.17085/apm.2017.12.1.91
- Author:
Yu Mi JU
1
;
Sang Ho SHIN
;
Shu Chung CHOI
;
Jin Young CHON
;
Choon Ho SUNG
;
Ho Sik MOON
Author Information
1. Department of Anesthesiology and Pain Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea. mhsjshgma@gmail.com
- Publication Type:Case Report
- Keywords:
Drug delivery systems;
Fibromyalgia;
Intrathecal injection;
Morphine
- MeSH:
Adult;
Analgesics, Opioid;
Antidepressive Agents, Tricyclic;
Cognitive Therapy;
Drug Delivery Systems*;
Education;
Exercise;
Female;
Fibromyalgia*;
Humans;
Injections, Spinal;
Morphine*;
Norepinephrine;
Pain, Intractable;
Pregabalin;
Serotonin
- From:Anesthesia and Pain Medicine
2017;12(1):91-94
- CountryRepublic of Korea
- Language:English
-
Abstract:
The fibromyalgia syndrome (FMS) could be approached by various treatments modalities including education, aerobic exercise, cognitive behavioral therapy, tricyclic antidepressants, serotonin norepinephrine reuptake inhibitors, pregabalin, and so on. If other treatments fail, opioids including morphine should be considered. In this case report, we describe the case of a 44-year-old woman who was diagnosed with FMS three years ago, and suffered from severe intractable pain, side effects from other drugs, and opioid tolerance. Administration of morphine via an implantable drug delivery system resulted in significant improvement in the patient's pain intensity, fibromyalgia impact questionnaire score, and sleep disturbance. Our case demonstrates that an implantable drug delivery system with morphine can be a potential treatment option for refractory fibromyalgia patients.