Scanning Electron Microscopic Study of the Eccrine Ostia of Mouse Foot Pads After Application of Antiperspirant.
10.3349/ymj.1983.24.2.123
- Author:
Sungnack LEE
1
;
Dong Sik BANG
;
Chung Koo CHO
Author Information
1. Department of Dermatology, Yonsei University College of Medicine, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
SEM;
Antiperspirant;
Eccrine Ostia
- MeSH:
Aluminum Hydroxide/pharmacology*;
Animal;
Eccrine Glands/drug effects*;
Foot;
Male;
Mice;
Mice, Inbred HRS;
Microscopy, Electron, Scanning;
Propantheline/pharmacology*;
Sweat Glands/drug effects*
- From:Yonsei Medical Journal
1983;24(2):123-126
- CountryRepublic of Korea
- Language:English
-
Abstract:
Recently, a topical preparation of 5% propantheline bromide and 10% aluminum hydroxychloride in an emulsion ground substance was introduced as an effective antiperspirant. According to the literature, aluminum salts may produce functional closure of swet ducts. Nevertheless, histologic study has as yet failed to reveal a solid anatomic basis for occlusion. In this study, the scanning electron microscope (SEM) was used to demonstrate eccrine gland ostial occlusion due to topical 5% propantheline bromide and 10% aluminum hydroxychloride.
