HLA-linked Genetic Markers in Koreans.
10.3349/ymj.1983.24.2.127
- Author:
Joo Deuk KIM
1
;
In Hong CHOI
;
Se Jong KIM
Author Information
1. Department of Microbiology, Yonsei University College of Medicine, Seoul, Korea.
- Publication Type:Original Article ; Comparative Study ; Research Support, Non-U.S. Gov't
- Keywords:
HLA;
Immunogenetics;
Glyoxalase I;
Properdin factor B, C2, C4;
Korean
- MeSH:
Caucasoid Race;
Comparative Study;
Genetic Markers*;
HLA Antigens/genetics*;
Human;
Korea;
Mongoloid Race*;
Polymorphism (Genetics)
- From:Yonsei Medical Journal
1983;24(2):127-131
- CountryRepublic of Korea
- Language:English
-
Abstract:
The polymorphic variants of HLA-linked genetic markers GLO, Bf, C2 and C4 were determined in Koreans. The GLO2 allele was found at a similar frequency as compared with other orientals and at higher frequency than in Caucasians. The gene frequencies of BfS and BfF showed different figures from those in other orientals and were similar to Caucasians. The C2C allele was the highest variant as in other populations. The rare variant C2A was not observed in this study. The common variants of C4A alleles are C4A*3 and C4A*4. Among the C4B variants, C4B*1, C4B*2 and C4B* QO are common in that order. Several undefined electrophoretic variants C4A and C4B were observed in this study. These findings suggest that the frequencies of various HLA-linked genetic markers can be used in anthropological studies.
