A Case of Vasculitis in Chronic Hepatitis C Patient Treated with Pegylated Interferon Alpha-2a and Ribavirin.
10.3350/kjhep.2007.13.3.419
- Author:
Youn Ho KIM
1
;
Woo Sik HAN
;
Sun Jae LEE
;
Sung Nam OH
;
Do Won CHOI
;
Kwan Soo BYUN
;
Jong Eun YEON
Author Information
1. Department of Internal Medicine, Korea University Medical College, Guro Hospital, Seoul, Korea. je_yeon@hotmail.com
- Publication Type:Case Report ; English Abstract
- Keywords:
Hepatitis C, chronic;
Peginterferon alfa-2a;
Vasculitis;
Skin
- MeSH:
Antiviral Agents/*adverse effects;
Drug Therapy, Combination;
Female;
Hepatitis C, Chronic/*drug therapy;
Humans;
Interferon Alfa-2a/*adverse effects;
Liver Function Tests;
Middle Aged;
Polyethylene Glycols/*adverse effects;
Ribavirin/*adverse effects;
Skin/drug effects;
Vasculitis/*chemically induced
- From:The Korean Journal of Hepatology
2007;13(3):419-422
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
There has been an increase in the number of patients treated with pegylated interferon (PEG-IFN) and ribavirin due to the better antiviral efficacy. The main serious adverse events of PEG-IFN plus ribavirin combination therapy are bone marrow suppression and hemolytic anemia. However, there are few reports of vasculitis occurring during PEG-IFN therapy. We describe a patient who developed vasculitis during the treatment of chronic hepatitis C with PEG-IFN and ribavirin.
