Crystalloid Resuscitation in Experimental Hemorrhagic Shock in Dogs.
10.4097/kjae.1993.26.4.658
- Author:
Sang Tae LEE
1
;
In Chan CHO
;
Young Chul PARK
;
Kyoo Sub CHUNG
Author Information
1. Department of Anesthesiology, St. Benedict Hospital, Pusan, Korea.
- Publication Type:Original Article
- Keywords:
Crystalloid;
Hemorrhage;
Cardiac output;
Oxygen content
- MeSH:
Animals;
Blood Gas Analysis;
Cardiac Output;
Natural Resources;
Dogs*;
Hemorrhage;
Lactic Acid;
Oxygen;
Partial Thromboplastin Time;
Perfusion;
Prothrombin Time;
Resuscitation*;
Shock, Hemorrhagic*;
Vascular Resistance
- From:Korean Journal of Anesthesiology
1993;26(4):658-665
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Although crystalloid solutions such as Ringer's lactate have become the standard for initial volume replacement after hemorrhage, it is controversy whether this fluid alone restores and maintains the depressed physiologic function after severe hemorrhage. Six anesthetized dogs were bled(35ml/kg) and resuscitated with Ringers lactate solution (100 ml/kg). Physiologic variables are measured initialy, after hemorrhage, after resucitation. Compared with initial value, after resuscitation data show marked reduction in hemoglobin, oxygen carrying capacity, vascular resistance, and electrolyte. But cardiac output and blood gas analysis data was not changed. Prothrombin time and partial thromboplastin time was prolongated. From this study crystalloid resuscitation in severe hemorrhagic shock restore cardiac output and perfusion, but fail to maintain adequate oxygen carrying capacity.
